Intrinsic Prism Frequently Asked Questions
Getting started
What is the Intrinsic Prism Comprehensive Toxin Test?
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Intrinsic Prism is a complete testing and guidance package—not only a laboratory test. The at-home profile measures 133+ toxin and detox markers, then combines the values with comprehensive AI analytics, detailed explanations, potential exposure causes, a personalized protocol, and 24/7 guidance.
Who is this test for?
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It is for adults who want a broader view of potential environmental exposures and detox-related pathways, plus practical help understanding what the findings may mean. Intrinsic Prism provides detailed results, potential exposure causes, a personalized protocol, and 24/7 guidance throughout the process.
How do I begin?
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Select Start Testing, enter the participant and shipping details, review the required agreements, and complete secure checkout. Your order then moves into kit fulfillment and collection guidance.
Can I order for another person?
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Yes. You can add participants during signup and keep a separate account email for another participant when needed. Each participant must have accurate identifying information for laboratory processing.
Is this a diagnosis?
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No. Laboratory findings do not diagnose a condition or identify a treatment by themselves. They should be interpreted alongside medical history, symptoms, examination, and other clinical information.
Exploring the test
What does the profile measure?
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The profile covers 133+ reported toxin and detox markers across five groups: mycotoxins, heavy metals, environmental toxins, PFAS chemicals, and toxin genetics. The complete searchable list is available on the What We Test page.
Why combine exposure markers with toxin genetics?
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Exposure markers and selected genetic variants answer different questions. Measured compounds can reflect what is being detected or excreted, while genetics may add context about pathways involved in biotransformation, antioxidant defense, methylation, metal handling, and DNA repair.
Why are urine, blood or serum, and DNA used?
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Different markers are best assessed in different specimen types. Urine is useful for many excreted compounds and is non-invasive to collect; blood or serum is used for the included PFAS chemistry; and DNA is used for stable inherited variants.
Does the test identify the exact source of an exposure?
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No. A detected marker does not, by itself, prove the exact product, building, food, workplace, or date that caused exposure. Source investigation requires history, timing, environment, and clinical context.
Does a result show current or past exposure?
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Some findings may reflect recent exposure, ongoing exposure, past exposure, storage, or current excretion. Results generally cannot establish the precise timing or duration of an exposure.
Why can toxin results change over time?
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Exposure, hydration, absorption, tissue storage, metabolism, excretion, season, and interventions can all change measured levels. A single result is a snapshot taken under the collection conditions of that day.
Why might very few toxins be detected?
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Low urinary detection may mean low exposure, but it can also relate to timing, tissue storage, urine concentration, metabolism, or kidney and liver function. A low result should not be interpreted as a complete guarantee of no exposure.
Preparing for testing
How should I prepare for collection?
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Follow the instructions included with your kit. Unless those collection instructions say otherwise, keep your usual routine so the sample reflects your normal state; Intrinsic Prism’s 24/7 guidance is available if you need help with the collection steps.
Should I fast before collecting urine?
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For the toxin urine collection, use the first-morning sample before eating or drinking unless your kit or provider gives different instructions. Requirements for any other specimen in your order may differ, so follow each included collection guide.
Should I stop medications or supplements?
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Do not stop prescribed medication without speaking to the prescribing clinician. Certain products can affect physiology or sample interpretation; follow the current kit instructions and ask your provider about methylene blue, NAC, binders, chelators, or active detox protocols.
Is provocation required?
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No. Provocation is not required. Because provocation agents, doses, timing, and reference ranges are not standardized, never begin a provocation or chelation protocol solely for collection without clinician direction.
How should I hydrate?
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Maintain normal hydration in the days before collection. Avoid deliberately over-drinking immediately before a urine sample because excessive dilution can affect sample integrity; severe dehydration can make a sample overly concentrated.
Can I drink coffee before the urine collection?
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Collect the first-morning urine before coffee, food, or other drinks when possible. Ask your ordering clinician if they want different conditions for your specific situation.
Can I collect while menstruating?
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Avoid collecting when blood may contaminate the urine. If collection cannot be postponed, contact support or your provider for current guidance; a careful mid-stream collection may be recommended.
Can I test during pregnancy or after pregnancy?
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Speak with your obstetric clinician and ordering provider before testing during pregnancy, nursing, or the postpartum period. Physiologic changes can affect interpretation, and no detoxification treatment should be started without appropriate medical supervision.
Collecting & shipping
What samples are required?
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Your kit and order instructions identify the required specimens for your selected profile. The comprehensive profile uses urine for many toxin markers, blood or serum for included PFAS markers, and DNA for selected genetic variants.
Why is first-morning urine recommended?
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A first-morning sample is collected after an overnight interval and helps standardize timing before food and drinks. Consistent collection conditions make results easier to interpret and compare.
What if my urine is unusually dilute or concentrated?
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Urine creatinine is used as a sample-quality and concentration check. A sample outside the laboratory’s reportable range may require recollection rather than producing a potentially misleading result.
What if I make a collection mistake?
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Pause and contact Intrinsic Prism before shipping. Do not guess, transfer material between containers, or relabel a specimen without support guidance. We will confirm whether the sample remains usable or needs recollection.
How do I return the kit?
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Use the packing and return instructions supplied in the kit. Confirm every required tube or container is labeled, sealed, and placed in the provided packaging before handing it to the specified carrier.
How long does the collection take?
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At-home portions are designed to be straightforward, while any blood collection depends on the collection option and location. Read the guide before starting so all labels, materials, and timing requirements are ready.
Understanding your results
When will my results be ready?
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Timing begins after all required specimens are received and accepted by the laboratory. Different specimen types can finish at different times; your complete report is released when the required components are available.
What will my report include?
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Your report organizes findings by panel, flags values against the laboratory’s reporting framework, and adds comprehensive AI analytics, readable explanations, potential exposure causes, and a detailed personalized protocol. 24/7 guidance is included to help you understand the report and follow your next steps.
How are reference ranges used?
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Reference ranges and decision limits are specific to the laboratory method, specimen, and population used to establish them. Results from another method or a provoked collection may not be directly comparable.
Does a flagged result mean I am sick?
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Not necessarily. A flag indicates how a measurement compares with the laboratory’s reporting framework. It does not establish a diagnosis, source, symptom cause, or treatment on its own.
Can I share results with my doctor?
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Yes. Your detailed report is designed to be shareable. Intrinsic Prism also includes comprehensive AI analytics, potential exposure causes, a personalized protocol, and 24/7 guidance so you have clear interpretation and next steps within the service.
What if a result is urgent or concerning?
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Use Intrinsic Prism’s 24/7 guidance for prompt help understanding the finding and your protocol. If you have severe or rapidly worsening symptoms or another emergency, seek urgent medical care rather than waiting for website support.
Retesting & next steps
When should I retest?
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Retesting should answer a defined question and use collection conditions that can be compared with the baseline. Timing depends on the exposure, intervention, clinical plan, and whether an exposure may still be ongoing.
How quickly do toxins clear?
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There is no single clearance timeline. It varies with the compound, dose, repeated exposure, tissue storage, genetics, liver and kidney function, and any clinician-supervised intervention.
Why can a level rise during an intervention?
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A higher urine level can reflect new exposure, changed hydration, natural variability, or increased mobilization and excretion. It should not automatically be treated as proof that an intervention failed or succeeded.
Should I start a detox protocol from the report alone?
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No. Treatment decisions should be individualized and clinician-supervised. Some interventions have risks, interactions, and contraindications, and the first priority may be identifying and reducing an ongoing exposure.
How can I make a future test comparable?
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Use the same specimen type and laboratory method, follow the same collection time and preparation instructions, and document major changes in diet, supplements, medications, exposure, hydration, and treatment.
Orders & payment
How much does the complete package cost?
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The Intrinsic Prism complete package is $1,999 per participant. The laboratory test supplies the values; the package also includes the at-home kit, comprehensive AI analytics, detailed result explanations with potential causes, a personalized protocol, and 24/7 guidance. The checkout summary shows the server-verified quantity and total before payment.
Is checkout secure?
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Yes. Address and payment details are collected in Stripe-hosted secure fields. Intrinsic Prism does not receive or store your full card number.
Can I use HSA or FSA funds?
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Eligibility depends on your plan and circumstances. Keep your receipt and confirm reimbursement requirements with your HSA or FSA administrator before relying on coverage.
What is the refund or cancellation policy?
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Eligibility can depend on order and kit status. Review the Refund Policy linked in the site footer and contact support as soon as possible if you need to change or cancel an order.
Privacy & support
How is my health information protected?
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Intrinsic Prism limits collection to information needed to process, support, and deliver the service and uses protected systems and service providers for checkout and laboratory workflows. Review the Privacy Policy for full details.
Who can see my results?
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Access is limited according to the service workflow, your authorizations, and applicable law. You control who you choose to share your report with outside those required services.
How do I correct participant or shipping information?
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Contact support as soon as you notice an error. Some information may be editable before fulfillment, while laboratory identity details require verification and cannot be casually changed after processing begins.
How can I get more help?
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Use Prism chat on the main site or the contact channel provided with your order. Your package includes 24/7 guidance for collection, understanding your detailed results and potential exposure causes, and working through your personalized protocol.
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