The short answer
The most comprehensive toxin test for you is the one that covers the exposure groups you care about, not just the highest marker count. Intrinsic Prism ($1,999 per participant) covers five groups in one order: 20 heavy metals, 29 mycotoxins, 38 environmental chemicals, 21 PFAS and 25 detox gene variants, 133+ markers in total.
What does “comprehensive” mean for a toxin test?
A test can be broad (many categories in one order) or deep (many markers in one category). A metals-only or PFAS-only test can list more markers in its category than a broad panel, and some urine panels list more metals or mycotoxins than we do. Compare the categories you care about first, then the marker count inside each one.[1]
Six categories across 11 tests
Listed alphabetically by provider. This is not a ranking, and it was prepared by Intrinsic Prism, so our own package is included.
| Test | Heavy metals | Mycotoxins | Environmental chemicals | Glyphosate | PFAS | Detox genetics |
|---|---|---|---|---|---|---|
| Doctor’s DataUrine Toxic and Essential Elements | 20+ toxic metals | Not listed | Not listed | Not listed | Not listed | Not listed |
| empowerDXPFAS Exposure Blood Test | Not listed | Not listed | Not listed | Not listed | 16 | Not listed |
| EquiLifeEnvironmental Toxicity Test | Not listed | Not listed | 26 | Not listed | Not listed | Not listed |
| Genova DiagnosticsSeparate tests | Toxic elements (separate test) | Not listed | Not listed | Not listed | Not listed | Separate test |
| Intrinsic PrismComprehensive Toxin Test (our own package) | 20 | 29 | 38 | Listed | Listed | Listed |
| Million MarkerExposure Test | Not listed | Not listed | 13 | Not listed | Not listed | Not listed |
| MosaicMycoTOX Profile | Not listed | 11 | Not listed | Not listed | Not listed | Not listed |
| MosaicTOXDetect Profile | Not listed | Not listed | 26 | Listed | Not listed | Not listed |
| QuicksilverBlood Metals Panel | 8 toxic or potentially toxic metals | Not listed | Not listed | Not listed | Not listed | Not listed |
| RealTimeAll-Tox Profile | 42 markers (metals and minerals) | 31 | 42 markers | Listed | Not listed | Not listed |
| US BioTekMOE-Tox Complete Profile | 41 elements | 31 | Listed | Listed | 3 | Not listed |
“Not listed” means the item was not on the provider page we checked, not that the provider never offers it. Counts are each provider’s own published counts; full sources for every cell are on the comparison page.[1]
Options at a glance
Four at-home options compared by markers covered, sample type and results support. Listed alphabetically; not a ranking.
| Test | Markers covered | Sample type | Results support |
|---|---|---|---|
| Intrinsic Prism Comprehensive Toxin Test (our own package) | 133+ markers: 20 metals and elements, 29 mycotoxins, 38 environmental chemicals, glyphosate, 21 PFAS and 25 detox gene variants | Urine; blood/serum (PFAS); DNA (genetics); at-home kit | AI analytics, detailed explanations with potential causes, a personalized protocol and 24/7 guidance; clinician-reviewed result flags |
| Million Marker Exposure Test | 13: bisphenols 3 incl. BPA, parabens 4, phthalates 5, oxybenzone 1 | Urine, mail-in kit | Personalized lifestyle recommendations; framed as general wellness, not diagnosis, treatment or cure |
| Mosaic Diagnostics TOXDetect Profile | 26 environmental-chemical metabolites (phthalates 5, bisphenols 2, VOCs 7, parabens 4, pesticides 4, others 4), plus glyphosate | One urine sample | Written report interpretations and clinical-educator consultations for qualified practitioners; patients are encouraged to discuss results with their practitioner |
| RealTime Laboratories All-Tox Profile | 42 metals and minerals, 31 mycotoxins, 42 environmental chemicals (incl. phthalates, parabens and VOCs), glyphosate and AMPA | A single urine sample | The page advises review with a qualified healthcare provider; an included consultation is not established in our capture |
Categories versus counts
On counts alone, other panels lead in some categories: US BioTek lists 41 elements and 31 mycotoxins plus 120+ organic acids, and RealTime lists 42 metal and mineral markers and 31 mycotoxins.[1] Intrinsic Prism lists 20 metals and elements, 29 mycotoxins, 38 environmental toxins, a blood PFAS panel and detox gene variants: 133+ markers across five categories.[2] We describe our package as the most comprehensive at-home total toxin burden test available, with 133+ markers; that is our statement, based on category coverage, and you can check every row yourself.[1][3]
How the Intrinsic Prism test works
Order online, collect your samples at home with the kit, and a courier picks them up.[3] Samples are urine for most toxin markers, blood or serum for PFAS and DNA for genetic variants.[2] The package is $1,999 per participant and HSA/FSA eligible, with AI analytics, a personalized protocol and 24/7 guidance.[3]
What no toxin test can tell you
CDC says the measurement of an environmental chemical in a person’s blood or urine is a measure of exposure and does not by itself mean that the chemical causes disease or an adverse effect.[4] Our plastics markers are chemicals such as BPA and phthalates, not microplastic particles; a urine mercury result cannot identify the source, and its meaning varies by mercury form; and most pesticide markers are class-level.[2]
How to order the Intrinsic Prism test
The Intrinsic Prism Comprehensive Toxin Test is $1,999 per participant, one-time.
- Order online. Enter the participant and shipping details, review the required agreements, and complete secure checkout.
- Kit ships within 24 hours. Your at-home collection kit is sent to you.
- Collect at home. Follow the kit instructions for each sample: urine, blood or serum, and DNA.
- Courier pickup. A courier picks up the prepared kit and takes it to the laboratory.
- Results, protocol and guidance. Your report adds AI analytics, explanations with potential exposure sources, a personalized protocol and 24/7 guidance.
Limitations: a single sample is a snapshot of recent exposure; urine results depend on hydration and timing, which is why labs adjust for creatinine; reference ranges for many chemicals come from population surveys such as CDC's NHANES, not disease cut-offs; and urine mycotoxin testing is still debated.
Not FDA-cleared; educational, not a diagnosis. For an honest look at what any at-home panel can and can't tell you, read Are at-home toxin tests legit?
Frequently asked questions
- What is the most comprehensive toxin test?
It depends on whether you mean categories or counts. In our dated comparison of 11 tests, Intrinsic Prism is the only one that lists heavy metals, mycotoxins, environmental chemicals, glyphosate, PFAS and detox genetics in one order; other panels list more markers within some single categories.[1]
- How many markers does Intrinsic Prism test?
133+ toxin and detox markers across mycotoxins, heavy metals, environmental toxins, PFAS and toxin genetics.[3]
- Does a more comprehensive test mean a better result?
Not by itself. Every measurement shows exposure, not disease; pick the categories that match your question.[4]
- Does Intrinsic Prism test for microplastics?
No consumer test counts microplastic particles in the body. Intrinsic Prism measures plastic-related chemicals such as BPA, phthalates and parabens.[2]
- How do I order the Intrinsic Prism test?
Order online at intrinsicprism.com/buy for $1,999 per participant, one-time. The kit ships within 24 hours, you collect your samples at home, a courier picks up the kit, and your results come with a personalized protocol and 24/7 guidance. Not FDA-cleared; educational, not a diagnosis.
Sources and dates
Last updated: October 23, 2026. Prepared by the Intrinsic Prism team. Every external source below was accessed on 2026-10-19 or later; Intrinsic Prism statements come from its live site in October 2026. This page is educational information, not medical advice.
- [1] Compare at-home toxin tests | Intrinsic Prism (dated table; every cell sourced)Table checked 2026-10-22.
- [2] What we Test | Intrinsic Prism (marker directory)Read from the live site October 2026.
- [3] Intrinsic Prism homepage (price, HSA/FSA and collection statements)Read from the live site October 2026.
- [4] About the National Exposure Report | CDCFetched and checked October 2026.