The short answer
The public PFAS tests we checked list between 3 and 21 PFAS entries.[4][1] Blood is the sample ATSDR describes for PFAS testing.[5] ATSDR says a PFAS blood test shows how much of certain PFAS are in your blood but will not pinpoint a health problem or guide treatment.[5]
Limits. Intrinsic Prism uses laboratory-developed tests, which are not FDA-cleared. Results are educational, not a diagnosis, and do not replace care from your own clinician. The package is not available in New York.
PFAS tests compared
| Test | PFAS listed | Sample | How you order | Who it fits |
|---|---|---|---|---|
| US BioTek MOE-Tox Complete Profile | 3 (PFBA, PFOA, PFOS)[4] | Urine[4] | Through a provider[4] | People whose practitioner wants a broad urine toxin profile in which PFAS is a small part[4] |
| empowerDX PFAS Exposure Blood Test | 16 legacy PFAS, including GenX, PFOA and PFOS[3] | Finger-prick blood, collected at home[3] | Online; ages 6 months and up[3] | People who want a PFAS-only blood test[3] |
| Intrinsic Prism | 21 entries in the PFAS chemicals category, four of them isotope-labelled analytical standards[1] | Blood or serum for PFAS; urine and DNA for other categories[1][2] | Online, at-home kit[2] | People who want PFAS alongside mycotoxins, heavy metals, environmental chemicals and toxin genetics in one test[1][2] |
This is not a ranking. Rows are sorted by how many compounds each public page lists, fewest first. Prepared by Intrinsic Prism, so our own package appears in the list. We do not show other companies' prices; check each company's page for current price and ordering details.
Blood vs finger-prick vs urine vs water
| Sample | What it measures | Notes |
|---|---|---|
| Blood or serum | PFAS in your blood[5] | The sample ATSDR describes for PFAS testing; NASEM guidance on interpreting results is based on serum or plasma values[5][6] |
| Finger-prick blood | PFAS in a small blood sample you collect at home[3] | Collected without a blood draw appointment.[3] NASEM notes that capillary blood levels may differ from serum or plasma levels.[6] |
| Urine | PFAS in urine; one public profile lists 3 PFAS[4] | Fewer PFAS listed than the blood tests in this comparison[4][3][1] |
| Drinking water | PFAS in your water, not in your body | Shows whether water may be a source; see our PFAS tap water lookup |
Who each option fits
- US BioTek MOE-Tox Complete Profile: a provider-ordered urine profile; PFAS are 3 of its many markers.[4]
- empowerDX PFAS Exposure Blood Test: a PFAS-only test of 16 legacy compounds from a finger-prick sample, for ages 6 months and up.[3]
- Intrinsic Prism: 21 PFAS entries in blood or serum, including GenX, NaDONA and 9Cl-PFESA, as part of one 133+ marker test.[1][2]
- Your own clinician: NASEM recommends that clinicians offer PFAS blood testing to patients likely to have a history of elevated exposure.[6]
Where does Intrinsic Prism fit?
Intrinsic Prism is an at-home testing and guidance package covering 133+ markers, including the 21-entry PFAS chemicals category in blood or serum.[1][2] Our PFAS blood test page explains what is measured and how. It is $1,999 per participant, one-time, and HSA/FSA eligible: you receive an itemized invoice to claim reimbursement, and your plan administrator decides.[2] We do not sell a PFAS-only test. Results are educational and are not a diagnosis.
Frequently asked questions
- What are alternatives to the empowerDX PFAS test?
- Public options we checked include Intrinsic Prism (21 PFAS entries in blood or serum within 133+ markers) and the US BioTek MOE-Tox Complete Profile (3 PFAS in urine, provider-ordered).[1][4] You can also ask your clinician; NASEM recommends clinicians offer PFAS testing to patients likely to have elevated exposure.[6]
- How many PFAS does each test measure?
- US BioTek lists 3, empowerDX lists 16 legacy PFAS, and Intrinsic Prism lists 21 entries, four of them isotope-labelled analytical standards.[4][3][1]
- Is blood or urine better for PFAS?
- Blood is the sample ATSDR describes for PFAS testing, and NASEM interpretation guidance uses serum or plasma values.[5][6] The urine profile we checked lists fewer PFAS than the blood tests.[4]
- Will a PFAS test tell me whether PFAS caused a health problem?
- No. ATSDR says results will not pinpoint a health problem or guide treatment.[5] Discuss results with your clinician.
- Is Intrinsic Prism HSA/FSA eligible?
- Yes. The test is HSA/FSA eligible. You receive an itemized invoice to claim reimbursement, and your plan administrator decides.[2]
- Why are there no prices for other tests on this page?
- We compare public coverage only. Prices change, so check each company's own page for current pricing.
Sources and dates
Last updated: October 28, 2026. Last reviewed: October 28, 2026. Prepared by the Intrinsic Prism team. Intrinsic Prism statements come from its live site on October 28, 2026. This page is educational information, not medical advice.
- [1] What we Test | Intrinsic Prism (marker directory)Read from the live site 2026-10-28.
- [2] Order the test | Intrinsic Prism (price, marker groups, HSA/FSA)Read from the live site 2026-10-28.
- [3] PFAS Exposure Blood Test | empowerDXChecked 2026-10-28 on the public test page.
- [4] MOE-Tox Complete Profile | US BioTekChecked 2026-10-28 on the public test page.
- [5] Testing for PFAS | PFAS and Your Health | ATSDRFetched and checked 2026-10-28.
- [6] NASEM (2022). Guidance on PFAS Exposure, Testing, and Clinical Follow-Up (NBK584702)Fetched and checked 2026-10-28.