The short answer
A PFAS blood test measures how much of certain PFAS are in your blood. Our kit uses a blood or serum sample for the PFAS markers, alongside urine and DNA samples for the other categories in the same 133+ marker test.[2][3] ATSDR says results show how much of certain PFAS are in your blood but will not give clear information about health effects, pinpoint a health problem or guide treatment.[4]
Limits. Intrinsic Prism uses laboratory-developed tests, which are not FDA-cleared. Results are educational, not a diagnosis, and do not replace care from your own clinician. The package is not available in New York.
What does the PFAS blood test measure?
The PFAS chemicals category on What we Test lists 21 entries (blood or serum), four of them isotope-labelled analytical standards that the laboratory adds to check the measurement.[1] The PFAS measured include:
- Legacy long-chain PFAS: PFOA, PFOS, PFHxS, PFNA, PFDA (PFDeA), PFUnA, PFDoA, PFTrDA, PFTeDA and PFHpS.[1]
- Shorter-chain PFAS: PFBA, PFPeA, PFHxA and PFHpA.[1]
- Replacement PFAS: GenX (HFPO-DA), NaDONA (ADONA) and 9Cl-PFESA (a major F-53B component).[1]
Long-chain PFAS bind proteins and can persist, so a serum value estimates longer-term internal burden. Shorter-chain PFAS clear faster, so a single sample may miss past peaks.[1] See the full list on What we Test.
PFAS blood test vs urine vs water test
| Test | What it measures | What it can and can't tell you |
|---|---|---|
| PFAS blood (serum) test | PFAS in your blood or serum[4] | How much of certain PFAS are in your body; not health effects, a diagnosis or treatment guidance[4] |
| Urine test | Our kit does not use urine for PFAS; urine is used for many other toxin markers[3] | Not the sample our kit uses for PFAS[3] |
| Water test | PFAS in drinking water, not in your body | Whether your water may be a source; ATSDR suggests asking your local health department about PFAS in your water[5] |
Check public water results first with our free PFAS tap water ZIP code lookup, then decide whether you also want to test your body.
How to prepare
- Follow the kit instructions for each sample: urine, blood or serum, and DNA.[2]
- How the blood or serum sample is collected depends on the collection option and location.[3]
- For the urine part of the same kit, see how to prepare for a urine toxin test.
Price, HSA/FSA and shipping
- $1,999 per participant, one-time. One all-in-one test: every test page on this site sells this same kit.[2]
- HSA/FSA eligible. You receive an itemized invoice to claim reimbursement from your plan; your plan administrator decides. See how to claim.
- Free US shipping. Ships worldwide to most countries; availability is confirmed at checkout.[6]
Frequently asked questions
- Can I do a PFAS blood test at home?
- Yes. You order online, the kit is sent to you and you follow the kit instructions for each sample: urine, blood or serum, and DNA.[2] How the blood or serum sample is collected depends on the collection option and location.[3]
- Which PFAS does the test measure?
- 21 entries in the PFAS chemicals category, four of them isotope-labelled analytical standards. They include PFOA, PFOS, PFHxS, PFNA, PFDA, GenX (HFPO-DA), NaDONA and 9Cl-PFESA.[1]
- Why blood instead of urine for PFAS?
- Blood or serum is used for the included PFAS chemistry.[3] Long-chain PFAS bind proteins and can persist, so serum estimates longer-term internal burden.[1]
- Will a PFAS blood test tell me whether PFAS caused a health problem?
- No. ATSDR says results will not give clear information about health effects, pinpoint a health problem, guide treatment, or predict or rule out future problems.[4] Discuss results with your clinician.
- Can I buy only the PFAS test?
- No. The PFAS markers are part of one test: $1,999 per participant, one-time, covering 133+ markers across mycotoxins, heavy metals, environmental chemicals, PFAS and toxin genetics.[2]
- Is the PFAS blood test HSA/FSA eligible?
- The test is HSA/FSA eligible. You receive an itemized invoice to claim reimbursement from your plan, and your plan administrator decides.[2]
- Does this test check my water for PFAS?
- No. It measures PFAS in your blood or serum. For water, use our PFAS tap water lookup; ATSDR suggests asking your local health department about PFAS in your water.[5]
Sources and dates
Last updated: October 28, 2026. Last reviewed: October 28, 2026. Prepared by the Intrinsic Prism team. Intrinsic Prism statements come from its live site on October 28, 2026. This page is educational information, not medical advice.
- [1] What we Test | Intrinsic Prism (marker directory)Read from the live site 2026-10-28.
- [2] Order the test | Intrinsic Prism (price, marker groups, HSA/FSA)Read from the live site 2026-10-28.
- [3] FAQ | Intrinsic PrismRead from the live site 2026-10-28.
- [4] Testing for PFAS | PFAS and Your Health | ATSDRFetched and checked 2026-10-28.
- [5] Perfluoroalkyls ToxFAQs | ATSDRFetched and checked 2026-10-28.
- [6] Shipping and delivery | Intrinsic PrismRead from the live site 2026-10-28.